INTELLECTUAL PROPERTY PORTFOLIO The Group owns or exclusively licenses a broad intellectual property (IP) portfolio of granted patents, patent applications, trade secrets and trademarks protecting INOVIQ’s technologies, products, processes and brands. The Group had 21 granted patents, 15 patents pending and 2 international provisional patent applications as at 30 June 2024, covering its SubB2M, Molecular NET, BARD1 and hTERT technologies and products across key jurisdictions including the United States, Europe, Asia, and Australia. Additionally, it owns registered trademarks for INOVIQ®, EXO-NET® and Acuris®. INOVIQ filed several provisional patent applications to expand its exosome intellectual property (IP) portfolio during the period: › An Australian Provisional Patent Application (APPA) was filed in October 2023 covering its NEURO-NET technology for isolation of brain-derived exosomes for biomarker discovery and diagnostic development. The APPA covers compositions for capturing extracellular vesicles derived from various brain cells in a sample and uses for commercial applications. › An APPA was filed in March 2024 covering its cutting-edge EXO-ACE technology for large scale isolation of exosomes for therapeutic use. The APPA covers compositions for use in capturing extracellular vesicles for large scale commercial applications. 13 Annual Report 2024 Review of Operations Patent Family Title Granted Pending Expiry SubB2M PCT/AU2017/051230 (WO2018/085888) Subtilase cytotoxin B subunit mutant AU, EP, JP, US BR, CA, CN, IN, KR, US (cont) 2037 US 2038 PCT/AU2022/050470 (WO2022/236383) Methods of analysing a sample US 2042 US7078489 Cytotoxin with subtilaise domain US BARD1 PCT/FR01/02731 (WO2002/018536) Truncated BARD1 protein, and its diagnostic and therapeutic uses US 2024 PCT/IB2011/054194 (WO2012/038932) Kits for detecting breast or ovarian cancer in a body fluid sample and use thereof EP, US, US (cont) 2031 US and US (cont) 2032 EP14002398.7 Non-coding RNA as diagnostic marker and treatment target US 2035 hTERT PCT/AU2015/050060 (WO2015/120523) Method of resolving inconclusive cytology to detect cancer AU, CN, EP, IL, JP, US US (cont) 2035 PCT/AU2016/050764 (WO2017/027928) Method of detecting cancer in morphologically normal cells US 2036 Molecular NETs PCT/US2010/058086 (WO2011/066449) Devices for detection of analytes CN, US (cont1), US cont2), US (cont3) US (cont6) 2030 US (cont1) 2033 US (cont2&3) 2031 PCT/US2013/049779 (WO2014/011673) Molecular Nets EP 2033 PCT/AU2022/050428 (WO2022/232886) Methods relating to tumourderived extracellular vesicles CN, EP, JP, SG, KR, US 2042 AU2023903359 Extracellular vesicle compositions and uses thereof AU (provisional) 2044 Therapeutic Evs AU2024900609 Resin compositions and methods of use AU (provisional) 2024 cont = continuation; div = divisional
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